rs113062739

This variant is located in the LDLRAD4 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

gut microbiome measurement

Bonder MJ et al. The effect of host genetics on the gut microbiome. Nature Genetics 48(11):1407-1412 (2016)
Allele A
OR 5.54
p 3.0e-8
N 984
Small GWAS
European

About LDLRAD4

Enables R-SMAD binding activity. Involved in negative regulation of cell migration; negative regulation of epithelial to mesenchymal transition; and negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway. Located in early endosome membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all LDLRAD4 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…