rs113155897

This variant is located in the KIF5A gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

receptor tyrosine-protein kinase erbb-3 measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele A

OR 0.54

p 1.0e-17

N 47,745

Large GWAS

European

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ClinVar annotation

Likely Benign★★★☆

10 submitters2 publications

Hereditary spastic paraplegia 10; Spastic paraplegia; not provided; Hereditary spastic paraplegia; not specified; KIF5A-related disorder

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About KIF5A

This gene encodes a member of the kinesin family of proteins. Members of this family are part of a multisubunit complex that functions as a microtubule motor in intracellular organelle transport. Mutations in this gene cause autosomal dominant spastic paraplegia 10. [provided by RefSeq, Jul 2008]

View all KIF5A variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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