rs113362373

This is a 3 prime utr variant variant in the UBXN2A gene.

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

red blood cell density

Chen MH et al. “Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.” Cell 182(5):1198-1213.e14 (2020)

Allele G

OR —

p 1.0e-53

N 727,624

Large GWAS

multi-ancestry

lymphocyte percentage of leukocytes

Vuckovic D et al. “The Polygenic and Monogenic Basis of Blood Traits and Diseases.” Cell 182(5):1214-1231.e11 (2020)

Allele G

OR 0.03

p 2.0e-18

N 408,112

Large GWAS

European

hemoglobin measurement

Chen MH et al. “Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.” Cell 182(5):1198-1213.e14 (2020)

Allele G

OR —

p 1.0e-17

N 746,431

Large GWAS

multi-ancestry

About UBXN2A

Predicted to enable ubiquitin binding activity. Involved in negative regulation of ERAD pathway and positive regulation of protein catabolic process. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Jul 2025]

View all UBXN2A variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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