rs113394050

This is a regulatory region variant variant in the RGS22 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

skin neoplasm

Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)

Allele C

OR 0.13

p 2.0e-20

N 670,929

Large GWAS

multi-ancestry

About RGS22

Enables G-protein alpha-subunit binding activity. Predicted to be involved in negative regulation of signal transduction. Located in actin cytoskeleton; cytosol; and fibrillar center. [provided by Alliance of Genome Resources, Jul 2025]

View all RGS22 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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