rs113849338

This is a synonymous variant in the PLCXD3 gene — it does not change the protein's amino acid sequence.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

growth hormone receptor measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele A

OR 0.24

p 2.0e-15

N 47,745

Large GWAS

European

About PLCXD3

Predicted to enable phosphoric diester hydrolase activity. Predicted to be involved in lipid catabolic process and signal transduction. Predicted to be located in cytoplasm. Predicted to be active in glutamatergic synapse. [provided by Alliance of Genome Resources, Jul 2025]

View all PLCXD3 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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