rs114785138

This is a protein-altering variant in the TLCD2 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

metabolite measurement

Tahir UA et al. “Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals.” Nature Communications 13(1):4923 (2022)

Allele G

OR 1.13

p 1.0e-52

N 2,466

Large GWAS

multi-ancestry

About TLCD2

Involved in several processes, including membrane assembly; phospholipid homeostasis; and regulation of membrane lipid distribution. Located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all TLCD2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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