rs115523707
This is a intron variant variant in the SPEF2 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
pulse pressure measurement, self reported educational attainment
de las Fuentes L et al. “Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci.” Molecular Psychiatry 26(6):2111-2125 (2021)
Allele T
OR 2.73
p 7.0e-9
N 81,032
Meta-analysisLarge GWAS
multi-ancestry
About SPEF2
Involved in sperm axoneme assembly. Located in cytosol; nuclear body; and sperm flagellum. Implicated in spermatogenic failure 43. [provided by Alliance of Genome Resources, Jul 2025]
View all SPEF2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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