rs11557080

This is a 3 prime utr variant variant in the RAB29 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Parkinson disease

Pan H et al. “Genome-wide association study using whole-genome sequencing identifies risk loci for Parkinson's disease in Chinese population.” Npj Parkinson's Disease 9(1):22 (2023)
Allele G
OR 0.21
p 1.0e-24
N 4,450
Large GWAS
East Asian
Nalls MA et al. “Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies.” The Lancet. Neurology 18(12):1091-1102 (2019)
Allele G
OR 0.13
p 3.0e-22
N 482,730
Meta-analysisLarge GWAS
European

About RAB29

Enables several functions, including dynein complex binding activity; guanyl ribonucleotide binding activity; and kinesin binding activity. Involved in several processes, including positive regulation of T cell receptor signaling pathway; positive regulation of receptor recycling; and retrograde transport, endosome to Golgi. Located in several cellular components, including Golgi apparatus; endosome; and nucleus. [provided by Alliance of Genome Resources, Jul 2025]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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