rs11557467
This is a protein-altering variant in the ZPBP2 gene.
▶Research that mentions this SNP (1)
▶Allergy and glioma risk: Test of association by genotypeAssociationN=5,548Sara E. Dobbins et al.(2011)· International Journal of Cancer
Case-control genome-wide association study of 1,878 glioma cases and 3,670 controls examining associations between asthma/allergy susceptibility variants and glioma risk. SNP rs7216389 at 17q21 (ORMDL3) was significantly associated with increased glioma risk (OR=1.10, 95% CI: 1.01-1.19, P=0.022), providing genetic evidence for a positive association between asthma susceptibility and glioma risk, contrary to epidemiological studies reporting inverse associations.
About ZPBP2
Predicted to be involved in acrosome assembly and binding activity of sperm to zona pellucida. Predicted to act upstream of or within membrane lipid metabolic process and regulation of gene expression. Located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
View all ZPBP2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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