rs11604175
This is a downstream gene variant variant in the VSIG2 gene.
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
v-set and immunoglobulin domain-containing protein 2 measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.18
p 3.0e-178
N 47,745
Large GWAS
European
endothelial cell-selective adhesion molecule measurement
Thareja G et al. “Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations.” Human Molecular Genetics 32(6):907-916 (2023)
Allele T
OR 0.26
p 9.0e-15
N 2,935
Large GWAS
Greater Middle Eastern (Middle Eastern, North African or Persian)
diastolic blood pressure
Keaton JM et al. “Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.” Nature Genetics 56(5):778-791 (2024)
Allele T
OR 0.10
p 2.0e-9
N 1,028,980
Large GWAS
multi-ancestry
blood protein amount
Gudjonsson A et al. “A genome-wide association study of serum proteins reveals shared loci with common diseases.” Nature Communications 13(1):480 (2022)
Allele T
OR 0.19
p 1.0e-20
N 5,353
Large GWAS
European
Emilsson V et al. “Co-regulatory networks of human serum proteins link genetics to disease.” Science (new York, N.y.) 361(6404):769-773 (2018)
Allele T
OR 0.19
p 3.0e-12
N 3,200
Large GWAS
European
About VSIG2
Predicted to be involved in lipid metabolic process. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all VSIG2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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