rs11607355
This is a downstream gene variant variant in the JAML gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
lung carcinoma
Byun J et al. “Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer.” Nature Genetics 54(8):1167-1177 (2022)
Allele T
OR 0.08
p 1.0e-21
N 70,156
Meta-analysisLarge GWAS
multi-ancestry
About JAML
Enables integrin binding activity and protein homodimerization activity. Involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules and myeloid leukocyte migration. Located in bicellular tight junction; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all JAML variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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