rs11613331
This is a intron variant variant in the SLC6A13 gene.
▶GWAS Catalog Trait Associations (11)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (11)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
deoxycarnitine measurement
Feofanova EV et al. “Whole-Genome Sequencing Analysis of Human Metabolome in Multi-Ethnic Populations.” Nature Communications 14(1):3111 (2023)
Allele A
OR 0.31
p 1.0e-100
N 10,457
Large GWAS
multi-ancestry
1-methyl-4-imidazoleacetate measurement
Feofanova EV et al. “Whole-Genome Sequencing Analysis of Human Metabolome in Multi-Ethnic Populations.” Nature Communications 14(1):3111 (2023)
Allele A
OR 0.30
p 7.0e-80
N 8,250
Large GWAS
multi-ancestry
pyroglutamine measurement
Surendran P et al. “Rare and common genetic determinants of metabolic individuality and their effects on human health.” Nature Medicine 28(11):2321-2332 (2022)
Allele A
OR 0.18
p 4.0e-68
N 14,296
Large GWAS
European
Feofanova EV et al. “Whole-Genome Sequencing Analysis of Human Metabolome in Multi-Ethnic Populations.” Nature Communications 14(1):3111 (2023)
Allele A
OR 0.17
p 1.0e-28
N 9,014
Large GWAS
multi-ancestry
Shin SY et al. “An atlas of genetic influences on human blood metabolites.” Nature Genetics 46(6):543-550 (2014)
Allele A
OR 0.04
p 2.0e-25
N 7,800
Large GWAS
European
Yin X et al. “Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci.” Nature Communications 13(1):1644 (2022)
Allele A
OR 0.14
p 2.0e-14
N 6,136
Large GWAS
European
body height
Yengo L et al. “A saturated map of common genetic variants associated with human height.” Nature 610(7933):704-712 (2022)
Allele A
OR 0.01
p 2.0e-35
N 5,314,291
Large GWAS
European, Hispanic or Latin American, East Asian, African unspecified, South Asian
3-aminoisobutyrate measurement
Schlosser P et al. “Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine.” Nature Genetics 55(6):995-1008 (2023)
Allele A
OR 0.38
p 4.0e-34
N 4,911
Large GWAS
European
Feofanova EV et al. “Whole-Genome Sequencing Analysis of Human Metabolome in Multi-Ethnic Populations.” Nature Communications 14(1):3111 (2023)
Allele A
OR 0.16
p 4.0e-17
N 6,347
Large GWAS
multi-ancestry
imidazole lactate measurement
Feofanova EV et al. “Whole-Genome Sequencing Analysis of Human Metabolome in Multi-Ethnic Populations.” Nature Communications 14(1):3111 (2023)
Allele A
OR 0.18
p 3.0e-29
N 8,199
Large GWAS
multi-ancestry
1-ribosyl-imidazoleacetate measurement
Chen Y et al. “Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases.” Nature Genetics 55(1):44-53 (2023)
Allele A
OR 0.15
p 8.0e-25
N 8,205
Large GWAS
European
imidazole propionate measurement
Chen Y et al. “Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases.” Nature Genetics 55(1):44-53 (2023)
Allele A
OR 0.13
p 1.0e-16
N 7,776
Large GWAS
European
urinary metabolite measurement
Schlosser P et al. “Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans.” Nature Genetics 52(2):167-176 (2020)
Allele G
OR 0.45
p 5.0e-15
N 1,221
Large GWAS
Calvo-Serra B et al. “Urinary metabolite quantitative trait loci in children and their interaction with dietary factors.” Human Molecular Genetics 29(23):3830-3844 (2021)
Allele G
OR 0.32
p 3.0e-12
N 996
Small GWAS
European
beta-aminoisobutyric acid measurement
Granot-Hershkovitz E et al. “Genetic loci of beta-aminoisobutyric acid are associated with aging-related mild cognitive impairment.” Translational Psychiatry 13(1):140 (2023)
Allele A
OR 0.17
p 6.0e-12
N 3,863
Large GWAS
multi-ancestry
About SLC6A13
Enables gamma-aminobutyric acid:sodium:chloride symporter activity. Involved in amino acid import across plasma membrane and monocarboxylic acid transport. Located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all SLC6A13 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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