rs116159732
This is a intron variant variant in the COPG1 gene.
▶Research that mentions this SNP (1)
▶Genetic variants in microRNA and microRNA biogenesis pathway genes and breast cancer risk among women of African ancestryAssociationN=9,670Frank Qian et al.(2016)· Human Genetics
This case-control study examined 822 genetic variants in primary miRNA sequences and 10,468 variants in 38 miRNA biogenesis pathway genes in relation to breast cancer risk among women of African ancestry. The study included 1,657 cases and 2,029 controls from the ROOT consortium with replication in 3,153 cases and 2,831 controls from the AABC consortium. Key findings identified SNPs associated with overall breast cancer risk and estrogen receptor (ER)-specific risk, including rs73991220 in mir-4725 (ER-negative; OR=1.27, p=0.002), rs146287903 in PAPD4 (ER-negative; OR=0.49, p=3.27×10⁻⁴), and rs72631820 in miR-339-3p (ER-positive; OR=1.36, p=0.004).
About COPG1
Predicted to enable structural molecule activity. Predicted to be involved in several processes, including Golgi vesicle transport; establishment of Golgi localization; and organelle transport along microtubule. Located in Golgi apparatus. Implicated in immunodeficiency 128. [provided by Alliance of Genome Resources, Jul 2025]
View all COPG1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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