rs11631214

This is a intron variant variant in the ADPGK gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Tinnitus

Clifford RE et al. Genetic architecture distinguishes tinnitus from hearing loss. Nature Communications 15(1):614 (2024)
Allele A
OR 5.74
p 1.0e-8
N 596,905
Large GWAS
multi-ancestry

About ADPGK

ADPGK (EC 2.7.1.147) catalyzes the ADP-dependent phosphorylation of glucose to glucose-6-phosphate and may play a role in glycolysis, possibly during ischemic conditions (Ronimus and Morgan, 2004 [PubMed 14975750]).[supplied by OMIM, Mar 2008]

View all ADPGK variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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