rs116863980

This is a intron variant variant in the PALM gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

lung adenocarcinoma

Shi J et al. “Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population.” Nature Communications 14(1):3043 (2023)

Allele A

OR 1.21

p 3.0e-9

N 42,315

Large GWAS

East Asian

About PALM

This gene encodes a member of the paralemmin protein family. The product of this gene is a prenylated and palmitoylated phosphoprotein that associates with the cytoplasmic face of plasma membranes and is implicated in plasma membrane dynamics in neurons and other cell types. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]

View all PALM variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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