rs11704827
This is a intron variant variant in the MICAL3 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
forced expiratory volume
Wain LV et al. “Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.” Nature Genetics 49(3):416-425 (2017)
Allele T
OR 0.03
p 8.0e-13
N 48,943
Large GWAS
European
Wain LV et al. “Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank.” The Lancet. Respiratory Medicine 3(10):769-81 (2015)
Allele T
OR 0.14
p 2.0e-9
N 29,303
Major Consortium StudyLarge GWAS
European
About MICAL3
Enables actin binding activity and molecular adaptor activity. Involved in actin filament depolymerization. Located in several cellular components, including Flemming body; intercellular bridge; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
View all MICAL3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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