rs117068593

GWAS Catalog Trait Associations (21)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

appendicular lean mass

Allele T
OR 0.04
p 9.0e-62
N 450,243
Major Consortium StudyLarge GWAS
European

platelet crit

Allele T
OR 0.03
p 2.0e-29
N 394,642
Large GWAS
European
Vuckovic D et al. The Polygenic and Monogenic Basis of Blood Traits and Diseases. Cell 182(5):1214-1231.e11 (2020)
Allele T
OR 0.03
p 5.0e-24
N 408,112
Large GWAS
European

osteopontin measurement

Allele T
OR 0.08
p 3.0e-29
N 47,745
Large GWAS
European

serum albumin amount

Allele T
OR 0.04
p 1.0e-28
N 928,679
Large GWAS
multi-ancestry
Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.03
p 6.0e-28
N 450,015
Large GWAS
multi-ancestry
Sakaue S et al. A cross-population atlas of genetic associations for 220 human phenotypes. Nature Genetics 53(10):1415-1424 (2021)
Allele T
OR 0.03
p 4.0e-28
N 435,807
Large GWAS
multi-ancestry

wnt inhibitory factor 1 measurement

Allele T
OR 0.06
p 3.0e-23
N 47,745
Large GWAS
European

alkaline phosphatase measurement

Allele T
OR 0.02
p 9.0e-21
N 394,642
Large GWAS
European

platelet volume

Allele T
OR 0.02
p 5.0e-20
N 394,642
Large GWAS
European

neutrophil count

Sakaue S et al. A cross-population atlas of genetic associations for 220 human phenotypes. Nature Genetics 53(10):1415-1424 (2021)
Allele T
OR 0.03
p 1.0e-18
N 432,666
Large GWAS
multi-ancestry

whole body water mass

Allele T
OR 0.01
p 2.0e-18
N 394,642
Large GWAS
European

leukocyte quantity

Sakaue S et al. A cross-population atlas of genetic associations for 220 human phenotypes. Nature Genetics 53(10):1415-1424 (2021)
Allele T
OR 0.03
p 5.0e-17
N 504,825
Large GWAS
multi-ancestry
Vuckovic D et al. The Polygenic and Monogenic Basis of Blood Traits and Diseases. Cell 182(5):1214-1231.e11 (2020)
Allele T
OR 0.02
p 4.0e-13
N 408,112
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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