rs11711421
This is a downstream gene variant variant in the NT5DC2 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
memory performance
Lahti J et al. “Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning.” Molecular Psychiatry 27(11):4419-4431 (2022)
Allele T
OR 6.07
p 1.0e-9
N 28,909
Large GWAS
European
cataract
Choquet H et al. “A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects.” Nature Communications 12(1):3595 (2021)
Allele T
OR 0.96
p 1.0e-8
N 538,515
Meta-analysisLarge GWAS
European
About NT5DC2
Predicted to enable 5'-nucleotidase activity. Predicted to be involved in negative regulation of dopamine biosynthetic process; negative regulation of oxidoreductase activity; and negative regulation of peptidyl-serine phosphorylation. Located in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]
View all NT5DC2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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