rs117169628
This variant is located in the SLC22A31 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
lysosome-associated membrane glycoprotein 3 measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele A
OR 0.08
p 1.0e-29
N 47,745
Large GWAS
European
COVID-19
“A first update on mapping the human genetic architecture of COVID-19.” Nature 608(7921):E1-E10 (2022)
Allele A
OR 1.09
p 3.0e-8
N 2,861,299
Large GWAS
multi-ancestry
Pairo-Castineira E et al. “GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.” Nature 617(7962):764-768 (2023)
Allele A
OR 1.20
p 3.0e-16
N 1,779,771
Meta-analysisLarge GWAS
multi-ancestry
Diz-de Almeida S et al. “Novel risk loci for COVID-19 hospitalization among admixed American populations.” Elife 13 (2024)
Allele A
OR 0.10
p 2.0e-15
N 73,303
Large GWAS
multi-ancestry
Kousathanas A et al. “Whole-genome sequencing reveals host factors underlying critical COVID-19.” Nature 607(7917):97-103 (2022)
Allele A
OR 1.20
p 4.0e-9
N 48,880
Large GWAS
European
▶ClinVar annotation
Benign★★★☆
2 submitters1 publicationAbout SLC22A31
Predicted to enable transmembrane transporter activity. Predicted to be involved in monoatomic ion transport and transmembrane transport. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all SLC22A31 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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