rs11718982
This is a downstream gene variant variant in the QRICH1 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
cognitive function measurement, self reported educational attainment
Demange PA et al. “Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction.” Nature Genetics 53(1):35-44 (2021)
Allele C
OR 0.06
p 1.0e-10
N 257,700
Large GWAS
European
intelligence
Schoeler T et al. “Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline.” Nature Communications 16(1):4524 (2025)
Allele C
OR 0.03
p 2.0e-10
N 254,641
Large GWAS
European
About QRICH1
Enables DNA binding activity. Involved in intracellular signal transduction; positive regulation of DNA-templated transcription; and positive regulation of apoptotic process. Located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
View all QRICH1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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