rs11761528
This variant is located in the ZKSCAN5 gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
testosterone measurement
Sinnott-Armstrong N et al. “Genetics of 35 blood and urine biomarkers in the UK Biobank.” Nature Genetics 53(2):185-194 (2021)
Allele T
OR 0.07
p 4.0e-52
N 322,594
Major Consortium StudyLarge GWAS
multi-ancestry
hormone measurement
Zhai G et al. “Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms.” Plos Genetics 7(4):e1002025 (2011)
Allele T
OR 0.16
p 3.0e-36
N 14,846
Large GWAS
European
body mass index
Pulit SL et al. “Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.” Human Molecular Genetics 28(1):166-174 (2019)
Allele T
OR 0.02
p 6.0e-14
N 806,834
Meta-analysisLarge GWAS
European
About ZKSCAN5
This gene encodes a zinc finger protein of the Kruppel family. The protein contains a SCAN box and a KRAB A domain and may be involved in transcriptional regulation. A similar protein in mouse is differentially expressed in spermatogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
View all ZKSCAN5 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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