rs11789015

This variant is located in the BARX1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

esophageal adenocarcinoma, digestive system disease, Barrett's esophagus

Levine DM et al. “A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.” Nature Genetics 45(12):1487-93 (2013)

Allele A

OR 1.20

p 1.0e-9

N 7,135

Large GWAS

European

About BARX1

This gene encodes a member of the Bar subclass of homeobox transcription factors. Studies of the mouse and chick homolog suggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The protein may also be associated with differentiation of stomach epithelia. [provided by RefSeq, Jul 2008]

View all BARX1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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