rs11808092

This is a variant in the EVI5 gene that changes a glutamine to an histidine.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Epstein Barr virus nuclear antigen 1 IgG measurement, multiple sclerosis

Zhou Y et al. Genetic loci for Epstein-Barr virus nuclear antigen-1 are associated with risk of multiple sclerosis. Multiple Sclerosis (houndmills, Basingstoke, England) 22(13):1655-1664 (2016)
Allele A
OR
p 2.0e-8
N 23,253
Large GWAS
multi-ancestry

ClinVar annotation

Benign☆☆☆
2 submitters2 publications

not specified

View on ClinVar →

About EVI5

Enables GTPase activator activity and small GTPase binding activity. Involved in positive regulation of GTPase activity and retrograde transport, endosome to Golgi. Located in cytosol. [provided by Alliance of Genome Resources, Jul 2025]

View all EVI5 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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