rs11847351

This variant is located in the PRKD1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

serum IgM amount

Jonsson S et al. “Identification of sequence variants influencing immunoglobulin levels.” Nature Genetics 49(8):1182-1191 (2017)

Allele A

OR —

β 0.070

p 5.0e-8

N 14,442

Large GWAS

European

About PRKD1

The protein encoded by this gene is a serine/threonine protein kinase involved in many cellular processes, including Golgi body membrane integrity and transport, cell migration and differentiation, MAPK8/JNK1 and Ras pathway signaling, MAPK1/3 (ERK1/2) pathway signaling, cell survival, and regulation of cell shape and adhesion. [provided by RefSeq, Jan 2017]

View all PRKD1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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