rs11931532
This is a intron variant variant in the BST1 gene.
▶Research that mentions this SNP (1)
▶Association of GWAS loci with PD in ChinaAssociationN=1,146Xue‐Li Chang et al.(2011)· American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
Case-control study of 636 Parkinson's disease patients and 510 controls from mainland China investigating SNPs at four genome-wide association study loci. SNCA (rs894278, OR=1.33) and LRRK2 (rs2046932, OR=1.98) variants increased PD risk, while PARK16 variants (rs823156, OR=0.73; rs6532194, OR=0.60) reduced risk. BST1 SNPs showed no significant association.
About BST1
Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008]
View all BST1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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