rs11956224

This is a intron variant variant in the DNAJC18 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

heart failure

Lee DSM et al. “Common-variant and rare-variant genetic architecture of heart failure across the allele-frequency spectrum.” Nature Genetics 57(4):829-838 (2025)

Allele A

OR 0.02

p 6.0e-10

N 2,358,556

Large GWAS

multi-ancestry

About DNAJC18

Predicted to enable Hsp70 protein binding activity. Predicted to be involved in cellular response to misfolded protein and chaperone cofactor-dependent protein refolding. Located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2025]

View all DNAJC18 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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