rs12100561
This variant is located in the EFCAB11 gene.
▶Research that mentions this SNP (1)
▶Genetic Variations at Loci Involved in the Immune Response Are Risk Factors for Hepatocellular CarcinomaAssociationN=1,159Robert J. Clifford et al.(2010)· Hepatology
Genome-wide association study identifying genetic variations affecting hepatocellular carcinoma (HCC) susceptibility in Korean populations. Strong associations found with CNV at T-cell receptor loci (TRA@, TRG@; P < 1×10^-15) and SNPs in MHC class II regions (rs9267673, rs2647073, rs3997872). Antigen presentation and processing pathway showed highly significant association (P = 1×10^-11). TPTE2 SNP rs2880301 distinguished HCC from cirrhosis (P = 1.74×10^-12).
About EFCAB11
Predicted to enable calcium ion binding activity and enzyme regulator activity. Predicted to be involved in microtubule cytoskeleton organization. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
View all EFCAB11 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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