rs12134493
This is a regulatory region variant variant.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
migraine disorder
Choquet H et al. “New and sex-specific migraine susceptibility loci identified from a multiethnic genome-wide meta-analysis.” Communications Biology 4(1):864 (2021)
Allele A
OR 1.11
p 6.0e-36
N 889,018
Meta-analysisLarge GWAS
European
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele A
OR 0.13
p 6.0e-12
N 394,626
Large GWAS
European
Anttila V et al. “Genome-wide meta-analysis identifies new susceptibility loci for migraine.” Nature Genetics 45(8):912-917 (2013)
Allele A
OR 1.14
p 5.0e-14
N 118,710
Meta-analysisLarge GWAS
European
Headache
Meng W et al. “A Genome-Wide Association Study Finds Genetic Associations with Broadly-Defined Headache in UK Biobank (N=223,773).” Ebiomedicine 28:180-186 (2018)
Allele A
OR 0.01
p 2.0e-10
N 223,782
Major Consortium StudyLarge GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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