rs12135071
This is a downstream gene variant variant in the TNN gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
serum creatinine amount
Jee YH et al. “Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.” Nature Communications 16(1):4935 (2025)
Allele T
OR 0.01
p 2.0e-8
N 928,679
Large GWAS
multi-ancestry
About TNN
Predicted to enable integrin binding activity. Involved in positive regulation of sprouting angiogenesis; regulation of cell adhesion; and regulation of cell migration. Located in collagen-containing extracellular matrix. Part of tenascin complex. [provided by Alliance of Genome Resources, Apr 2025]
View all TNN variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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