rs121434429
This is a variant in the FCER1G gene that changes a serine to an proline.
▶ClinVar annotation
Pathogenic★★★☆
4 submitters4 publicationsMitochondrial complex 1 deficiency, nuclear type 6
View on ClinVar →About FCER1G
The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors. [provided by RefSeq, Jul 2008]
View all FCER1G variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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