rs12191751

This is a regulatory region variant variant in the SUPT3H gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

body mass index, osteoarthritis

Zhang L et al. “A sex- and site-specific relationship between body mass index and osteoarthritis: evidence from observational and genetic analyses.” Osteoarthritis and Cartilage 31(6):819-828 (2023)

Allele T

OR —

p 3.0e-12

N 1,633,524

Large GWAS

European

About SUPT3H

Enables transcription coactivator activity. Involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of SAGA complex and transcription factor TFTC complex. [provided by Alliance of Genome Resources, Jul 2025]

View all SUPT3H variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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