rs12202969

This is a intron variant variant.

▶

GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

alcohol consumption quality

Saunders GRB et al. “Genetic diversity fuels gene discovery for tobacco and alcohol use.” Nature 612(7941):720-724 (2022)

Allele A

OR 0.01

p 2.0e-24

N 2,965,643

Large GWAS

European, East Asian, Hispanic or Latin American, African unspecified

bipolar I disorder

Mullins N et al. “Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.” Nature Genetics 53(6):817-829 (2021)

Allele G

OR 0.92

p 1.0e-12

N 475,038

Large GWAS

European

risk-taking behaviour

Karlsson Linnér R et al. “Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.” Nature Genetics 51(2):245-257 (2019)

Allele A

OR 0.01

p 1.0e-11

N 975,353

Large GWAS

European

bipolar disorder

Mühleisen TW et al. “Genome-wide association study reveals two new risk loci for bipolar disorder.” Nature Communications 5:3339 (2014)

Allele A

OR 1.12

p 1.0e-8

N 24,025

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…