rs12242
This is a protein-altering variant in the APMAP gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
cystatin-F measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.33
p 1.0e-32
N 10,708
Large GWAS
European
blood protein amount
Gudjonsson A et al. “A genome-wide association study of serum proteins reveals shared loci with common diseases.” Nature Communications 13(1):480 (2022)
Allele C
OR 0.42
p 3.0e-32
N 5,353
Large GWAS
European
About APMAP
Enables arylesterase activity. Located in cell surface and membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all APMAP variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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