rs12258286
This is a intron variant variant in the PNLIPRP1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
level of pancreatic lipase-related protein 1 in blood serum
Surapaneni A et al. “Identification of 969 protein quantitative trait loci in an African American population with kidney disease attributed to hypertension.” Kidney International 102(5):1167-1177 (2022)
Allele T
OR 0.61
p 8.0e-15
N 466
Small GWAS
African American or Afro-Caribbean
About PNLIPRP1
Predicted to enable calcium ion binding activity; lipoprotein lipase activity; and phospholipase A1 activity. Predicted to be involved in several processes, including cholesterol homeostasis; high-density lipoprotein particle remodeling; and triglyceride catabolic process. Predicted to be located in extracellular region. Biomarker of prostate cancer. [provided by Alliance of Genome Resources, Jul 2025]
View all PNLIPRP1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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