rs12305809
This is a intron variant variant in the ZNF268 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
type 2 diabetes mellitus
Vujkovic M et al. “Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis.” Nature Genetics 52(7):680-691 (2020)
Allele G
OR 0.03
p 1.0e-12
N 1,114,458
Meta-analysisLarge GWAS
European
About ZNF268
Predicted to enable DNA binding activity and DNA-binding transcription factor activity. Involved in several processes, including positive regulation of non-canonical NF-kappaB signal transduction; regulation of apoptotic process; and regulation of primary metabolic process. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 2025]
View all ZNF268 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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