rs12315211
This is a downstream gene variant variant in the PUS7L gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
gut microbiome measurement, allergen exposure measurement
Stickley SA et al. “Gene-by-environment interactions modulate the infant gut microbiota in asthma and atopy.” The Journal of Allergy and Clinical Immunology 156(2):433-448 (2025)
Allele A
OR 0.06
p 1.0e-14
N 688
Small GWAS
multi-ancestry
About PUS7L
Enables pseudouridine synthase activity. Involved in mRNA pseudouridine synthesis. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
View all PUS7L variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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