rs12340838
This is a intron variant variant in the HSDL2 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
estrogen-receptor negative breast cancer, chronotype measurement
Wu X et al. “Using human genetics to understand the phenotypic association between chronotype and breast cancer.” Journal of Sleep Research 33(3):e13973 (2024)
Allele A
OR —
p 3.0e-8
N 577,176
Large GWAS
European
About HSDL2
Predicted to enable oxidoreductase activity. Involved in cholesterol homeostasis. Located in mitochondrion and peroxisome. [provided by Alliance of Genome Resources, Jul 2025]
View all HSDL2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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