rs12415148

This is a upstream gene variant variant.

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

chromosome, telomeric region length

Dorajoo R et al. “Loci for human leukocyte telomere length in the Singaporean Chinese population and trans-ethnic genetic studies.” Nature Communications 10(1):2491 (2019)

Allele T

OR 0.20

p 3.0e-25

N 16,759

Large GWAS

multi-ancestry

Wen S et al. “Comparative analysis of the Mexico City Prospective Study and the UK Biobank identifies ancestry-specific effects on clonal hematopoiesis.” Nature Genetics 57(3):572-582 (2025)

Allele T

OR 0.15

p 2.0e-19

N 9,598

Major Consortium StudyLarge GWAS

Hispanic or Latin American

erythrocyte count

Jee YH et al. “Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.” Nature Communications 16(1):4935 (2025)

Allele T

OR 0.03

p 1.0e-19

N 928,679

Large GWAS

multi-ancestry

Ovarian cyst

Pujol Gualdo N et al. “Atlas of genetic and phenotypic associations across 42 female reproductive health diagnoses.” Nature Medicine 31(5):1626-1634 (2025)

Allele T

OR 0.86

p 9.0e-9

N 232,058

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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