rs12440869
This variant is located in the IQCH gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
left ventricular diastolic function measurement
Wild PS et al. “Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function.” The Journal of Clinical Investigation 127(5):1798-1812 (2017)
Allele T
OR 0.73
p 1.0e-8
N 21,852
Large GWAS
European
About IQCH
Predicted to act upstream of or within lncRNA transcription and single fertilization. Predicted to be active in nuclear speck. [provided by Alliance of Genome Resources, Jul 2025]
View all IQCH variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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