rs12445022
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
small vessel stroke
Mishra A et al. “Stroke genetics informs drug discovery and risk prediction across ancestries.” Nature 611(7934):115-123 (2022)
Allele A
OR 1.11
p 1.0e-9
N 1,517,518
Large GWAS
multi-ancestry
Traylor M et al. “Genetic variation at 16q24.2 is associated with small vessel stroke.” Annals of Neurology 81(3):383-394 (2017)
Allele A
OR 1.16
p 3.0e-9
N 14,560
Large GWAS
European
caudate nucleus volume
Satizabal CL et al. “Genetic architecture of subcortical brain structures in 38,851 individuals.” Nature Genetics 51(11):1624-1636 (2019)
Allele A
OR 5.87
p 4.0e-9
N 37,741
Large GWAS
multi-ancestry
stroke
Traylor M et al. “Genetic basis of lacunar stroke: a pooled analysis of individual patient data and genome-wide association studies.” The Lancet. Neurology 20(5):351-361 (2021)
Allele A
OR 1.13
p 3.0e-8
N 254,959
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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