rs12449568
This is a intron variant variant in the ANKFN1 gene.
▶Research that mentions this SNP (1)
▶Genome-wide association scan for stature in Chinese: evidence for ethnic specific lociAssociationN=3,571Shu-Feng Lei et al.(2009)· Human Genetics
Genome-wide association study in 618 Northern Chinese and replication in 2,953 Southern Chinese identified 13 contiguous SNPs in the ZNF510/ZNF782 region significantly associated with stature (P = 9.71×10^-5 to 3.11×10^-6, FDR q = 0.036-0.046). The most significant SNP rs10816533 replicated in Southern Chinese (P = 0.029, combined P = 1.55×10^-6), suggesting this is an ethnic-specific locus for height variation in Chinese populations.
About ANKFN1
Predicted to be involved in establishment of mitotic spindle orientation and regulation of establishment of bipolar cell polarity. Predicted to act upstream of or within behavioral fear response; equilibrioception; and locomotor rhythm. Predicted to be active in spindle. [provided by Alliance of Genome Resources, Jul 2025]
View all ANKFN1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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