rs12453394
This variant is located in the UBE2Z gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
type 2 diabetes mellitus
Bonàs-Guarch S et al. “Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.” Nature Communications 9(1):321 (2018)
Allele A
OR 1.07
p 3.0e-8
N 168,420
Large GWAS
multi-ancestry
About UBE2Z
This gene encodes an enzyme which ubiquitinates proteins which participate in signaling pathways and apoptosis. [provided by RefSeq, Feb 2012]
View all UBE2Z variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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