rs12472790

GWAS Catalog Trait Associations (21)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

polyunsaturated fatty acid measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 1.0e-20
N 450,015
Large GWAS
multi-ancestry
Allele A
OR
p 8.0e-10
N 128,922
Large GWAS
European

omega-6 polyunsaturated fatty acid measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 3.0e-18
N 450,015
Large GWAS
multi-ancestry
Allele A
OR
p 4.0e-14
N 239,268
Large GWAS
European

choline measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 1.0e-17
N 450,015
Large GWAS
multi-ancestry

phosphoglycerides measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 3.0e-17
N 450,015
Large GWAS
multi-ancestry

level of phosphatidylcholine

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 2.0e-16
N 450,015
Large GWAS
multi-ancestry

total phospholipids in lipoprotein particles measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 4.0e-16
N 450,015
Large GWAS
multi-ancestry

esterified cholesterol measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 7.0e-16
N 450,015
Large GWAS
multi-ancestry

sphingomyelin measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 1.0e-15
N 450,015
Large GWAS
multi-ancestry

polyunsaturated fatty acids to total fatty acids percentage

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 2.0e-15
N 450,015
Large GWAS
multi-ancestry

total lipids in lipoprotein particles measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 6.0e-15
N 450,015
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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