rs12543725
This variant is located in the SLC45A4 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
birth weight
Horikoshi M et al. “Genome-wide associations for birth weight and correlations with adult disease.” Nature 538(7624):248-252 (2016)
Allele G
OR 0.02
p 2.0e-9
N 142,558
Large GWAS
multi-ancestry
Plotnikov D et al. “Association between birth weight and refractive error in adulthood: a Mendelian randomisation study.” The British Journal of Ophthalmology 104(2):214-219 (2020)
Allele G
OR 0.02
p 2.0e-9
N 188,039
Large GWAS
European
fetal genotype effect measurement, placenta mass
Beaumont RN et al. “Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth.” Nature Genetics 55(11):1807-1819 (2023)
Allele G
OR 0.03
p 9.0e-9
N 65,405
Large GWAS
European
About SLC45A4
Predicted to enable sucrose:proton symporter activity. Predicted to be involved in sucrose transport. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all SLC45A4 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…