rs12549902

GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

type 2 diabetes mellitus

Allele A
OR 1.08
p 2.0e-21
N 210,865
Large GWAS
East Asian
Allele A
OR 1.11
p 1.0e-12
N 41,646
Large GWAS
multi-ancestry

insulin response measurement

Prokopenko I et al. A central role for GRB10 in regulation of islet function in man. Plos Genetics 10(4):e1004235 (2014)
Allele A
OR 0.06
p 1.0e-8
N 5,372
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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