rs12649972

This variant is located in the ARHGAP10 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

alkaline phosphatase measurement

Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)

Allele T

OR 0.03

p 1.0e-31

N 463,178

Large GWAS

multi-ancestry

About ARHGAP10

Predicted to enable GTPase activator activity. Predicted to be involved in cytoskeleton organization and negative regulation of apoptotic process. Located in cytosol and endosome membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all ARHGAP10 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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