rs1265091

This is a downstream gene variant variant in the PSORS1C1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Thyroid stimulating hormone level

Teumer A et al. “Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.” Nature Communications 9(1):4455 (2018)

Allele T

OR 0.06

p 5.0e-15

N 54,288

Large GWAS

European

Zhou W et al. “GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer.” Nature Communications 11(1):3981 (2020)

Allele T

OR 0.06

p 5.0e-15

N 119,715

Large GWAS

European

About PSORS1C1

This gene is one of several genes thought to confer susceptibility to psoriasis and systemic sclerosis, located on chromosome 6 near the major histocompatibility complex (MHC) class I region. [provided by RefSeq, Sep 2011]

View all PSORS1C1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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