rs12651106

This is a intron variant variant in the DCHS2 gene.

▶

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

circulating fibrinogen levels

Lovely RS et al. “Assessment of genetic determinants of the association of γ' fibrinogen in relation to cardiovascular disease.” Arteriosclerosis, Thrombosis, and Vascular Biology 31(10):2345-52 (2011)

Allele A

OR 0.14

p 2.0e-12

N 3,042

Large GWAS

About DCHS2

This gene encodes a large protein that contains many cadherin domains and likely functions in cell adhesion. Genome-wide association studies suggest that this gene may be important in Alzheimer's disease, compressive strength index, and appendicular lean mass. [provided by RefSeq, May 2017]

View all DCHS2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Loading comments…