rs12653396
▶GWAS Catalog Trait Associations (7)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (7)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
mathematical ability
Lee JJ et al. “Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.” Nature Genetics 50(8):1112-1121 (2018)
Allele A
OR 0.02
p 4.0e-24
N 811,539
Large GWAS
European
age at first sexual intercourse measurement
Mills MC et al. “Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour.” Nature Human Behaviour 5(12):1717-1730 (2021)
Allele T
OR 0.02
p 2.0e-21
N 397,338
Large GWAS
European
attention deficit hyperactivity disorder
Rajagopal VM et al. “Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention-deficit hyperactivity disorder.” Nature Genetics 54(8):1117-1124 (2022)
Allele T
OR 0.91
p 2.0e-11
N 53,181
Large GWAS
European
attention deficit hyperactivity disorder, educational attainment
Chen D et al. “Unraveling shared susceptibility loci and Mendelian genetic associations linking educational attainment with multiple neuropsychiatric disorders.” Frontiers in Psychiatry 14:1303430 (2023)
Allele A
OR —
p 4.0e-11
N 349,097
Large GWAS
European
taste liking measurement
May-Wilson S et al. “Large-scale GWAS of food liking reveals genetic determinants and genetic correlations with distinct neurophysiological traits.” Nature Communications 13(1):2743 (2022)
Allele A
OR 0.08
p 5.0e-10
N 156,509
Large GWAS
European
attention deficit hyperactivity disorder, caudate nucleus volume
Klein M et al. “Genetic Markers of ADHD-Related Variations in Intracranial Volume.” The American Journal of Psychiatry 176(3):228-238 (2019)
Allele A
OR 5.38
p 1.0e-9
N 67,146
Large GWAS
European
self reported educational attainment
Lee JJ et al. “Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.” Nature Genetics 50(8):1112-1121 (2018)
Allele A
OR 0.01
p 1.0e-13
N 1,131,881
Large GWAS
European
Demange PA et al. “Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction.” Nature Genetics 53(1):35-44 (2021)
Allele A
OR 0.05
p 5.0e-13
N 510,795
Large GWAS
European
Okbay A et al. “Genome-wide association study identifies 74 loci associated with educational attainment.” Nature 533(7604):539-42 (2016)
Allele A
OR —
β 0.013
p 8.0e-9
N 405,072
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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