rs1265565

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

diastolic blood pressure

Plotnikov D et al. “High Blood Pressure and Intraocular Pressure: A Mendelian Randomization Study.” Investigative Ophthalmology & Visual Science 63(6):29 (2022)

Allele T

OR 0.36

p 4.0e-58

N 526,001

Large GWAS

European

hemoglobin measurement

Timoteo VJ et al. “Common and ethnic-specific genetic determinants of hemoglobin concentration between Taiwanese Han Chinese and European Whites: findings from comparative two-stage genome-wide association studies.” The Journal of Nutritional Biochemistry 111:109126 (2023)

Allele T

OR —

β 0.044

p 1.0e-30

N 46,904

Large GWAS

European

venous thromboembolism

Zhou W et al. “Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease.” Cell Genomics 2(10):100192 (2022)

Allele T

OR 0.06

p 1.0e-9

N 1,063,277

Meta-analysisLarge GWAS

multi-ancestry

immunoglobulin isotype switching attribute

Jonsson S et al. “Identification of sequence variants influencing immunoglobulin levels.” Nature Genetics 49(8):1182-1191 (2017)

Allele T

OR —

β 0.070

p 3.0e-8

N 14,183

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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